Is whey protein or plant-based protein the better choice for your supplement line? This article breaks down the pros and cons of each option to help you decide what’s best for your brand’s growth!

Whey Protein vs. Plant Protein: Which One is Better?

By Rick
Handel
04/14/2025
Blog

Which is better, whey protein vs. plant protein? It depends on several factors which we’ll explore in this article.

But first, consider that the global whey protein market was valued at approximately $11.79 billion in 2023 and is projected to reach $22.63 billion by 2032 with a compounded annual growth rate (CAGR) of 7.5%.¹

Likewise, the value of the plant-based protein was estimated at $14.3 billion in 2024 and is projected to reach $20.5 billion by 2029 with a CAGR of 7.5%.²

Whether you’re exploring custom manufacturing or enhancing your current whey or plant protein product, both options are quite popular and in high demand among consumers.

Protein is an essential nutrient that is vital for sustaining biological processes and life itself. The word protein comes from the Greek word proteios, meaning “primary,” “first place,” or “of the first rank.” Its fundamental role in health and nutrition makes it a key component for everyone.³

Proteins play essential roles in human biochemistry. They form the foundation of body structures like skin and hair, support tissue, muscle, and bone repair, and can serve as an energy source. Proteins are also the building blocks of cellular enzymes—biological catalysts that accelerate chemical reactions in cells. Additionally, they are vital for hormone production, nutrient transport, and communication between cells, tissues, and organs. They strengthen the immune system, form digestive enzymes that break down food for absorption, and help regulate fluid and pH balance in the body.⁴ ⁵

Given the many vital functions of protein, choosing between plant-based and whey protein is a crucial decision when formulating your supplement products.

What is Plant-Based Protein?

What is plant-based protein made of? As the name suggests plant-based proteins are concentrates or isolates derived from protein-rich plants.

Popular plant-based proteins include soy, pea, brown rice, and hemp protein, each offering unique benefits:

Soy protein – The original plant-based protein in the dietary supplement industry, soy protein is rich in isoflavones, which provide additional health benefits.
Pea protein – A highly digestible plant protein known for promoting satiety and offering various nutritional advantages.
Brown rice protein – Considered hypoallergenic, this plant-based protein is reasonably complete and boasts excellent amino acid bioavailability.
Hemp protein – Sourced from the cannabis plant but free of THC, hemp protein is a sustainable option that thrives in diverse climates and has multiple uses across different industries.

To understand the difference between whey and plant protein, it’s important to know the terms complete protein and incomplete protein:

A complete protein contains all the essential amino acids in sufficient amounts.⁶
An incomplete protein lacks one or more of these amino acids.⁷

While whey protein and other animal-source proteins are all considered complete, plant-based proteins are considered incomplete. Nevertheless, apart from hemp protein, the others listed above had all compared favorably with the “gold standard”, whey protein.

Another option is to combine different plant proteins, allowing them to complement each other and balance out any missing amino acids.

How is Plant-Based Protein Made?

There are some similarities and differences in the way that one plant-based protein is made from another:

Soy protein – Soy protein is made by extracting protein from soybeans through a series of steps that include dehulling, flaking, and defatting. The resulting protein can be processed into soy flour, concentrates, or isolates.⁸
Pea protein – The steps involved in producing pea protein include dehulling, grinding and milling, extraction, separation, precipitation, washing and drying, and milling and powdering. At this point, the fine powder can be used as pea protein powder.⁹
Brown rice protein – Brown rice protein powder is made by milling brown rice grains, rehydrating them, and then treating them with enzymes to separate the protein from the carbohydrates. The protein is then isolated and powdered.¹⁰
Hemp protein – Hemp protein is made by grinding hemp seeds into a fine powder. The process involves cleaning, drying, and de-shelling the seeds, then pressing them to extract oil. The remaining meal is ground into a powder.¹¹

Health Benefits of Plant-Based Protein

When comparing plant-based protein vs. whey, one key advantage of plant-based proteins is their lower risk of causing allergies.

In contrast, milk-based proteins like whey and casein have higher allergenic potential. A national survey¹² of 51,819 U.S. households found that about 1 in 20 people reported an allergy to cow’s milk. The prevalence of cow’s milk allergy was found to be a substantial population-level burden including substantial healthcare utilization, psychosocial burden, and nutritional impacts—particularly among the approximately 30% of individuals with CMA who cannot tolerate baked forms of milk. It should also be noted that milk allergies are not the same thing as lactose intolerance.

A milk allergy is an immune system reaction to the proteins in milk, whereas lactose intolerance is a digestive issue where the body lacks the enzyme needed to break down the sugar (lactose) in milk. Milk allergy results in symptoms such as hives, wheezing, and in some cases, anaphylaxis. Lactose intolerance results in symptoms like bloating, gas, and diarrhea. Consequently, even a milk-based protein powder, such as whey protein, is free of lactose, its protein content can still result in an allergic reaction in some people.

The following are specific benefits associated with different plant-based proteins:

Soy protein – Helps induce thermogenesis¹³, increase bone mineral content and density in postmenopausal women¹⁴, promote healthy cholesterol levels already within a normal range¹⁵, and relieve vasomotor symptoms of menopause (hot flashes and night sweats)¹⁶ ¹⁷ ¹⁸ ¹⁹.
Pea protein – Helps induce thermogenesis²⁰, promote satiety²¹, maintain healthy blood pressure levels already within normal ranges²², and promote muscle growth²³.
Brown rice protein – Helps decrease fat mass, increase lean body mass, skeletal muscle hypertrophy, power, and strength.²⁴
Hemp protein – Helps maintain healthy blood pressure levels already within normal ranges²⁵, and provides antioxidant protection against oxidative stress²⁶.

What is Whey Protein?

Whey is a byproduct of cheese production, and whey protein is extracted from it. It typically contains a higher concentration of essential amino acids than many other protein sources.²⁷

Also, whey protein typically contains 24% branched-chain amino acids which are readily oxidized as an energy source during stress. In addition, whey protein is also a source of cysteine, a precursor to the vital intracellular antioxidant glutathione (GSH)²⁸, which is depleted by oxidative stress that occurs during exercise, infections, trauma, or major surgery.²⁹

There are three major forms of whey protein. These include whey concentrate, whey isolate, and whey hydrolysate:

Whey concentrate – This option generally provides about 80% protein. Typically, it is the least expensive of the three forms and will have a higher level of lactose which increases both sugar and carbohydrate levels in the protein.
Whey isolate – Whey protein isolate typically contains about 90% protein. It undergoes a filtration process that removes most of the fat and lactose, making it a leaner option compared to whey concentrate.
Whey hydrolysate – Whey hydrolysate contains about 85% protein and undergoes hydrolysis, a process that breaks down the protein for easier digestion and absorption. Made from whey isolate, it is also free of fat and lactose. However, it is the most expensive whey protein option.

How is Whey Protein Made?

Whey protein is made through a multistep process:

Milk collection – From high-quality cow’s milk.
Cheesemaking – During which enzymes separate the solid curds from the liquid whey.
Whey separation – Filtration removes fat and impurities.
Protein concentration – Further processing through membrane filtration or ion exchange.
Drying – Whey protein dried into powder.

To learn more about how proteins are manufactured, our Senior Formulator, Kevin Kumetz, recently wrote a detailed article on the protein powder manufacturing process.

Health Benefits of Whey Protein

There have been many studies on whey protein, especially whey protein isolate (WPI). These studies have demonstrated several different health benefits, among which are the following:

Digestibility – WPI is virtually fat- and lactose-free, is extremely digestible, and has a good taste. WPI does not tend to cause gas, bloating, or other gastrointestinal distress.³⁰
PDCAAS – WPI has received the highest score (1.14) of any protein tested according to the Protein Digestibility Corrected Amino Acid Score (PDCAAS), the preferred method for evaluating protein quality. And now, a recently developed fermented whey ingredient is taking protein quality to an even higher level, with an astounding PDCAAS of 1.20.³¹
Bodybuilding – Clinical research³² ³³ ³⁴ shows that taking 1.2-1.5 grams WPI per kilogram of body weight, per day in combination with strength training for 6-10 weeks increased lean body mass, strength, and muscle hypertrophy compared to placebo.
Fat loss – Studies³⁵ ³⁶ have shown that subjects using 20-29 g WPI lost significantly more body fat and significantly less lean muscle mass.
Glutathione – In clinical research³⁷, those who ingested 45 grams daily of WPI had the highest increase in glutathione (24%), a critical antioxidant.

Is Plant-Based Protein Better Than Whey Protein?

Is plant protein better than whey protein? Neither is truly better than the other. Both provide digestible, quality sources of protein that the body can use.

If you’re targeting customers who prefer vegan, plant-based sources, and/or who are allergic or otherwise sensitive to milk products, and/or who are concerned with environmental impact, then plant protein is the better choice. If these factors aren’t a concern, the best approach is to choose a protein source based on the specific benefits you want to highlight.

Difference Between Whey and Plant Protein

Besides what we’ve already discussed, there are some additional differences to consider between whey and plant proteins. These include taste and texture, nutritional content, and sustainability Briefly discuss the differences between whey and plant protein based on:

Taste and Texture

Due to its dairy origin, whey proteins typically have a creamier and smoother texture. Comparatively, plant proteins can have a grittier texture and earthier taste due to their origins from plant sources.

That being said, over the past few years, plant protein suppliers have become more adept at improving the texture and taste of those proteins. The best pea proteins have virtually eliminated any hint of “beany” taste.

Nutritional Content

Amino Acid Profiles: Although both provide similar protein content, whey has a higher concentration of BCAAs (about 26%) including leucine, isoleucine, and valine. Also, the amino acid profile is such that whey is considered a complete protein. Conversely, plant-based proteins contain lesser amounts of BCAAs (18-19%) and may require mixing with other plant proteins to achieve a better amino acid profile.
Calorie Count: Both have similar calorie counts, but plant protein tends to have slightly fewer calories.
Vitamins and Minerals: Plant-based proteins have a high nutrient density and may offer additional vitamins, minerals, fiber, and antioxidants, depending on the source. Whey protein may contain calcium, B-vitamins, and other vitamins & minerals in lesser amounts. At the end of the day, however, these other nutrients are not generally considered to be key factors in making a protein choice.

Sustainability and Ethics: Building a Brand with Purpose:

Whey protein comes from cow’s milk, while plant-based proteins do not contain animal products, making them suitable for vegetarians and vegans. Plant-based proteins generally have a significantly lower environmental impact compared to animal-based proteins, using less land and water, and producing fewer greenhouse gas emissions.³⁸

Concluding Thoughts

Both whey and plant-based proteins are experiencing significant global market growth. Since protein is essential for health and wellness, selecting the right type for your supplement products is crucial.

Each protein source offers unique benefits—plant-based proteins have lower allergenic potential and a smaller environmental impact, while whey protein provides a smoother, creamier texture.

When deciding between whey protein vs. plant protein, the best choice depends on your target audience. No matter which you choose, Vitaquest is here to help.

Manufacture High-Quality Protein Supplements with Vitaquest

Vitaquest is a contract development and manufacturing organization (CDMO) that has provided nutraceutical businesses with exceptional supplement research and development, powder supplement manufacturing, packaging design, powder, and particle engineering services using fluid bed, oscillation, and roller compaction technologies, and fulfillment solutions for over 45 years.

Whether you’re a newcomer to the industry or aiming to diversify your product range, Vitaquest possesses the expertise, cutting-edge facilities, and solutions needed to swiftly and effectively turn your plant-based protein or whey protein supplement concept into reality. Furthermore, you’ll receive an exceptional level of customer support.

Vitaquest also brings expertise in both domestic and international regulatory standards, along with a strong commitment to sustainability. Sourcing sustainable ingredients and utilizing eco-friendly manufacturing processes can enhance brand appeal. Our FDA cGMP compliance, along with third-party GMP certifications from NSF, USP, and others, assures brand owners and consumers that we meet the highest industry standards. Additionally, our ability to provide Kosher, Halal, and certified organic products—along with FSSC 22000 certification for food safety—demonstrates our dedication to manufacturing excellence.

Are you ready to capitalize on the trending market for whey and plant-based proteins? If so, call 800-526-9095 to speak with one of our knowledgeable sales executives or request a nutraceutical manufacturing price quote if you’ve already finalized your project requirements!

Request Pricing

Frequently Asked Questions About Plant-Based and Whey Protein

Q: Is plant protein harder to digest than whey?

No. Since plant proteins don’t contain lactose or dairy proteins, which many people have difficulty digesting, they are often easier to digest than whey protein. Even people who have problems digesting beans, peas, and other legumes can enjoy plant proteins because they don’t contain any of the offending sugars.

Q: Does pea protein build muscle like whey?

Human research³⁹ has shown that supplementation with pea protein promoted increased muscle thickness and was especially good for people starting or returning to muscular strengthening. Furthermore, no difference was seen between the effectiveness of pea protein and whey protein.

Q: What’s the best plant protein?

There are many effective plant proteins. One particularly good one is pea protein which may help with weight loss, promoting muscle growth, and maintaining healthy blood pressure levels already within normal ranges.

Q: Is plant protein inflammatory?

No. Research suggests there was a decreasing trend in inflammatory markers with the consumption of plant proteins compared to animal proteins.⁴⁰

Q: What are the downsides to plant protein powder?

There are no real “downsides” per se. Compared to dairy proteins, plant proteins can have a grittier texture and earthier taste, although, over the past few years, suppliers of plant proteins have become more adept at improving the sensory characteristics of those proteins.

References

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Claessens M, Calame W, Siemensma AD, Saris WH, van Baak MA. The thermogenic and metabolic effects of protein hydrolysate with or without a carbohydrate load in healthy male subjects. Metabolism. 2007 Aug;56(8):1051-9.
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Albertazzi P, Pansini F, Bonaccorsi G, Zanotti L, Forini E, De Aloysio D. The effect of dietary soy supplementation on hot flushes. Obstet Gynecol 1998; 91:6B11.
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Li H, Prairie N, Udenigwe CC, Adebiyi AP, Tappia PS, Aukema HM, Jones PJ, Aluko RE. Blood pressure lowering effect of a pea protein hydrolysate in hypertensive rats and humans. J Agric Food Chem. 2011 Sep 28;59(18):9854-60.
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Babault N, Païzis C, Deley G. et al. Pea proteins oral supplementation promotes muscle thickness gains during resistance training: a double-blind, randomized, Placebo-controlled clinical trial vs. Whey protein. J Int Soc Sports Nutr. 2015; 12:3. https://doi.org/10.1186/s12970-014-0064-5.
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Samsamikor M, Mackay DS, Mollard RC, Alashi AM, Aluko RE. Hemp seed protein and its hydrolysate compared with casein protein consumption in adults with hypertension: a double-blind crossover study. Am J Clin Nutr. 2024;120(1):56-65. doi:10.1016/j.ajcnut.2024.05.001.
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Farnfield MM, Trenerry C, Carey KA, Cameron-Smith D. Plasma amino acid response after ingestion of different whey protein fractions. Int J Food Sci Nutr. 2009 Sep;60(6):476-86.
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Cribb PJ, Wiliams AD, Carey MF, Hayes A. The effect of whey isolate and resistance training on strength, body composition, and plasma glutamine. Int J Sport Nutr Exerc Metab 2006;16:494-509.
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39
Babault N, Païzis C, Deley G. et al. Pea proteins oral supplementation promotes muscle thickness gains during resistance training: a double-blind, randomized, Placebo-controlled clinical trial vs. Whey protein. J Int Soc Sports Nutr. 2015; 12:3. https://doi.org/10.1186/s12970-014-0064-5.
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Rick

Handel

Senior Vice President of Commercial Operations

Rick Handel is a 50-year veteran of the nutraceutical industry, with a strong background in formulation, R&D and GMP manufacturing of dietary supplements. Rick is celebrating 30 years with industry-leading supplement manufacturer Vitaquest International, where he currently serves as Senior Vice President of Commercial Operations. In that capacity, Rick is responsible for driving sales and innovation by identifying and developing new strategies, business opportunities, science-backed ingredients, and novel delivery technologies. Rick holds eight patents and has presented his published scientific papers and studies at conferences around the world.

Exploring the Fall 2025 Supplement Trends for Brand Owners

VITAQUEST’S CONTRACT MANUFACTURING SERVICES

Latest on Manufacturing & Production

Exploring the Fall 2025 Supplement Trends for Brand Owners

VITAQUEST’S CONTRACT MANUFACTURING SERVICES

Latest on Manufacturing & Production

Whey Protein vs. Plant Protein: Which One is Better?

What is Plant-Based Protein?

How is Plant-Based Protein Made?

Health Benefits of Plant-Based Protein

What is Whey Protein?

How is Whey Protein Made?

Health Benefits of Whey Protein

Is Plant-Based Protein Better Than Whey Protein?

Difference Between Whey and Plant Protein

Taste and Texture

Nutritional Content

Sustainability and Ethics: Building a Brand with Purpose:

Concluding Thoughts

Manufacture High-Quality Protein Supplements with Vitaquest

Frequently Asked Questions About Plant-Based and Whey Protein

References

Rick

Handel

Senior Vice President of Commercial Operations

Subscribe Today to the Vitaquest Blog

Recent Posts

Exploring the Fall 2025 Supplement Trends for Brand Owners

Vitaquest is Audit Ready Every Day

Plant-Based Protein Benefits for Women’s Health

The Ins and Outs of Building an Effective Nutraceutical Supply Chain Strategy

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Share:

800-526-9095

Our Company

Our Services & Capabilities

Get In Touch

Exploring the Fall 2025 Supplement Trends for Brand Owners

VITAQUEST’S CONTRACT MANUFACTURING SERVICES

Latest on Manufacturing & Production

Exploring the Fall 2025 Supplement Trends for Brand Owners

VITAQUEST’S CONTRACT MANUFACTURING SERVICES

Latest on Manufacturing & Production

Whey Protein vs. Plant Protein: Which One is Better?

What is Plant-Based Protein?

How is Plant-Based Protein Made?

Health Benefits of Plant-Based Protein

What is Whey Protein?

How is Whey Protein Made?

Health Benefits of Whey Protein

Is Plant-Based Protein Better Than Whey Protein?

Difference Between Whey and Plant Protein

Taste and Texture

Nutritional Content

Sustainability and Ethics: Building a Brand with Purpose:

Concluding Thoughts

Manufacture High-Quality Protein Supplements with Vitaquest

Frequently Asked Questions About Plant-Based and Whey Protein

References

Rick

Handel

Senior Vice President of Commercial Operations

Subscribe Today to the Vitaquest Blog

Recent Posts

Exploring the Fall 2025 Supplement Trends for Brand Owners

Vitaquest is Audit Ready Every Day

Plant-Based Protein Benefits for Women’s Health

The Ins and Outs of Building an Effective Nutraceutical Supply Chain Strategy

Sign Up for Our Newsletter

Share:

800-526-9095

Our Company

Our Services & Capabilities

Get In Touch

Frequently Asked Questions About Plant-Based and Whey Protein