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Experienced Providers of Nutraceutical Contract Manufacturing Services

With over four decades of experience and thousands of satisfied customers, Vitaquest provides exceptional nutraceutical contract manufacturing services to owners of supplement businesses located in the USA and around the globe. Whether you’re just starting in the industry or a well-established brand, our team has the market insights, tools, and expertise to help you create a high-quality product.

Customized Supplement Development

Vitaquest’s in-house expert team is adept at turning your ideas into expertly formulated nutraceutical supplements. We primarily specialize in the custom manufacturing of capsules, powder, and tablet supplements.

Proven Manufacturing Process

Our state-of-the-art testing and supplement contract manufacturing facilities allow us to produce the highest-quality products that meet your customers’ needs and expectations. Our commitment to quality and compliance when converting quality ingredients into best-in-class marketable products means you don’t have to worry about the safety or efficacy of the products hitting the shelves.

Additionally, our expertise in particle creation, modification and manufacturing using oscillation, roll compaction, and fluid bed technologies is second to none. Our pilot and commercial scale manufacturing capabilities include wet and dry granulation, agglomeration, microencapsulation, particle sizing, air drying, and exacting mixing of liquid and powder components.

Our Facility Certifications

NSF Certified logo with text "GMP Registered Dietary Supplements"
Quality Assurance International certification seal.
FSSC 22000 Vitaquest certification logo in green, gray, and yellow.
Logo of Health Canada Natural Health Products Directorate.

Product Certifications We Offer

NSF Certification mark with text "GMP for Sport™ Registered"
Informed Manufacturer Certification logo
Orthodox Union certified kosher symbol.
Green and white Halal certification logo.

FSSC 22000 Certification

Vitaquest was the first contract supplement manufacturer in the USA to receive FSSC 22000 certification. FSSC 22000 Certification is a food safety certification for food manufacturers (including dietary supplement manufacturers). This certification is recognized by the Global Food Safety Initiative. It demonstrates our commitment to implementing industry best practices and safeguarding the health and well-being of consumers on a global level.

How Vitaquest Works as Your Contract Supplement Manufacturer 

START
Initial Consultation
Two professionals discussing over a computer in an office environment

Working with Vitaquest as your contract supplement manufacturer is a collaborative process. We start by understanding your supplement manufacturing needs and the unique expectations of the customer base you want to serve. This discussion is a crucial step in tailoring solutions custom-fit for your vision.

Formula Creation
Customized Formulation

After grasping your needs, our skilled R&D team will work with you to craft a customized supplement that is uniquely yours. Using precise amounts of the appropriate raw materials, we can design an evidence-based product with efficacy built in. This not only allows you to substantiate structure/function claims but also increases the likelihood of good repeat sales once consumers have initially used your product.

If readily available raw materials aren’t adequate for formulation, we can modify ingredient properties with our particle engineering capabilities, such as granulation, agglomeration, microencapsulation.

Ingredient Potency & Bioavailability
Selection of Raw Materials

A well-formulated dietary supplement requires the use of evidence-based ingredients to help ensure product efficacy.  Ingredients may be selected worldwide on the basis of quality, and in forms that provide high potency and bioavailability.  For example, many mineral supplements include well-absorbed mineral salts bonded to organic acids, including citrates, picolinates and gluconates. Likewise, formulas with herbal extracts may include standardized extracts with guaranteed amounts of the natural active or marker compounds within the herbs.

If readily available raw materials aren’t adequate for formulation, we can modify ingredient properties with our particle engineering capabilities, such as granulation, agglomeration, microencapsulation.

Production Kick-Off
P.O. Submission
Warehouse logistics 2

The real countdown begins once you, as the brand owner, submit the purchase order. At this point, Vitaquest can get to work on creating your product!

 

Logistics
Ordering the Raw Materials

Without question, this is the step that takes the longest in the manufacturing process. Why? Here’s an example. Let’s say that the raw material in question is a probiotic. As live microorganisms, probiotic ingredients are typically made to order. They literally must be grown on a natural medium, and that doesn’t happen overnight. In fact, growing probiotics may take 6 weeks or so. Now let’s say those probiotics come from overseas (which is often the case), so that means the ingredient must be shipped internationally—which could take 1-2 weeks, plus additional time for customs clearing. Fortunately, Vitaquest stocks dozens of tested and approved probiotic ingredients under refrigerated conditions, so there is often no need to wait for international shipments,

In addition to probiotics, Vitaquest stocks thousands of ingredients in its vast, climate-controlled warehouses, so they’ll be ready when needed to make your product.



Step into Manufacturing

Close-up of orange tablets being sorted by a supplement manufactuirng facility.

Production and Manufacturing

For over 45 years, we’ve been perfecting the craft of manufacturing and testing dietary supplements to ensure they consistently exceed our customer’s expectations. Today, we proudly create and produce over 4,000 custom formulas for more than 500 brands worldwide.

Scroll down to learn more about our best-in-class manufacturing process.

Our Contract Nutraceutical Manufacturing Process Vitaquest's Oversight and Quality

Vitaquest warehouse aisle with neatly stacked pallets of wrapped goods.

Raw Materials Arrival, Quarantine & Testing

Once the raw materials arrive at our facilities, cGMP regulations require that they be quarantined and tested before they are released into inventory. The type of testing required includes identity and potency, microbiological compliance, and heavy metal compliance.

Identity & Potency

To test for identity and potency, there must be an established methodology for testing the raw material ingredient. That methodology may exist in the U.S. Pharmacopeia or provided by some other credible source. Not only must that methodology be followed, but an authenticated sample of the ingredient (standard) will need to be used to validate a sample of the incoming raw material ingredient. The standard is used for comparison purposes. The raw material will be tested against the standard using appropriate laboratory equipment to see if it matches. Appropriate lab equipment may include Fourier Transform Infrared (FT-IR) Spectroscopy, Ultraviolet-visible (UV-VIS) Spectroscopy, Inductively Coupled Plasma – Mass Spectrometry (ICP-MS) and High-Performance Liquid Chromatography (HPLC). In this way, identity and potency can be established.

Microbiological Testing

The raw material must be tested for microbiological compliance to verify that it does not contain dangerous levels of microorganisms such as Salmonella, E. coli, yeast, or mold.

Professional performing microbiological tests in a lab setting.

Heavy Metal Testing

Finally, heavy metal testing for lead, mercury, cadmium, and arsenic may also be conducted. Vitaquest tests for conformance to the strict limits found in the United States Pharmacopeia (USP). If you are marketing your product in California, the state’s Proposition 65 limits are associated with some hefty fines if your product fails to meet their more stringent heavy metal requirements.

Bench Work

Once all the raw materials have been released into inventory, Vitaquest will conduct bench work, also known as an R&D batch. This is where the raw materials will all be mixed and a limited number of capsules (or other delivery form) will be produced in the lab to ascertain that the formulation will work in a finished dosage form. Depending upon the situation, Vitaquest may provide samples of the tablets/capsules/powder to the customer to evaluate. Once the customer approves the samples, we can then move on to the pilot batch.

Pilot Batch

Using what was learned during bench work, Vitaquest will run a pilot batch of the product on the actual production equipment. This is necessary to determine if the product will run correctly on the equipment during the production run. If there are any issues, the formulation may need to be adjusted, which may require approval by the brand owner. If everything goes well, Vitaquest will move on to the full production run.

Production Run & Testing

The production run is when the finished product will be produced. There are several steps in the process, including some additional testing that needs to be done. This may include uniformity of mix, content uniformity, disintegration testing, and a repeat of some of the tests done on the raw materials.

Scientist at Vitaquest performing quality assurance in a lab with advanced analytical equipment.

Uniformity of Mix

All the raw materials that comprise a given dietary supplement are mixed together in a large-scale commercial mixer. During this process, the raw materials must be completely and uniformly mixed to ensure an even distribution of each specified vitamin, mineral, herb, etc. (“nutrients”) throughout the entire batch.  A uniform mix is important since all the capsules, tablets, or powders will be made from a batch of raw materials to consistently have the proper, predetermined amount of nutrients in them. A sample of the mixed blend is taken to the lab, and the levels of certain ingredients are tested to verify that the mix is indeed uniform.

Content Uniformity

After determining that the mix is uniform, the next step is to ensure that each tablet and capsule has the correct weight to verify its nutrient potency.  This is known as “content uniformity.”  While capsules are being filled or tablets are being punched during the manufacturing process, their weight is regularly spot tested.  In addition, to capturing weight uniformity data, additional data regarding thickness and hardness is also recorded.  For both capsules and tablets, content uniformity is charted to ensure results within the specified range.  If for any reason, there is an unacceptable variation from the product specifications for content uniformity (weight, thickness, density), those capsules or tablets are rejected.

Fluid Bed Manufacturing

Our pilot and commercial scale manufacturing capabilities include wet and dry granulation, agglomeration, microencapsulation, particle sizing, air drying, and exacting mixing of liquid and powder components. These processes are required when content uniformity is essential.

Lab technician conducting quality checks in Vitaquest lab.

Disintegration Testing

Disintegration testing involves placing a capsule or tablet in temperature-controlled water, simulating digestive muscle action through agitation. If disintegration occurs within the time allowed in the assay protocol, there’s confidence it will similarly disintegrate in the human digestive tract, making its nutrients ready for absorption.

Stability Testing

If an expiration date appears on the label of a product, regulations state that the date should be supported by science. The best way to do this is to conduct stability testing. This testing, which is available from Vitaquest as a contract service, helps identify which nutrients are most vulnerable to damage and to what degree potency is affected.  By accounting for such variables as specific ingredients, dosage form, packaging, and storage conditions, it can determine how much of an increase in the potency for a given nutrient is needed to compensate for potency losses over time.  There are two types of stability testing: 1) accelerated stability, and 2) ambient stability.

Accelerated Stability

During accelerated stability, a dietary supplement in its intended packaging is placed inside an environmental chamber that controls temperature (typically 40°C) and relative humidity (typically 75% RH).  This chamber will create conditions that are designed to accelerate the normal aging of a product.  For example, if a product spends 12 weeks in the accelerated chamber, it may be the approximate equivalent of two years of aging time at room temperature.  When the product is removed from the stability chamber, we can then test it for potency loss and other effects.

Ambient (Real Time) Stability

Ambient stability is determined by taking a sample of packaged product we manufacture and holding it in a retain room under controlled, ambient conditions of temperature (25°C) and relative humidity (60% RH).  The retain room is used to correlate and confirm shelf-life results from accelerated testing.  At regular intervals during its shelf life, a product is pulled from the retain room and tested for potency which is then compared to the accelerated aging studies.

Testing of Finished Products

Once the finished capsules/tablets/powders from the first commercial production batch have been made, similar tests to those done on the raw materials are performed, including microbiological and heavy metal compliance. Vitaquest will then produce a certificate of analysis (COA) which will be sent to the brand owner. Once the brand owner approves the COA, the finished product can be shipped to the customer’s distribution facility, and the manufacturing process is complete.

We are committed to delivering the highest quality standards in every supplement we manufacture, from integrating cutting-edge manufacturing and testing technologies in the manufacturing process to adhering to every industry regulation.

Lab technician in protective gear inspecting machinery in a sterile environment.

Transparent Communication

Communication is the cornerstone of our custom supplement contract manufacturing solutions. We focus on open and transparent communication, ensuring everyone is on the same page at every stage. Your Vitaquest Client Services associate will be your single point of contact, communicating all pertinent information to you as it becomes available.

Timely Delivery

We are committed to delivering products on time. Our expert internal teams will work with Client Services to ensure you do not have to worry about missing deadlines when bringing your products to market.

Post-Production Support

Vitaquest goes above and beyond conventional contract supplement manufacturing, offering ongoing support beyond supplement manufacturing solutions. This includes regulatory assistance, packaging design services, order fulfillment, third-party logistics, and more.

Let Us Custom Manufacture a High-Quality Dietary Supplement for You.

Request a competitive manufacturing price quote from Vitaquest today!

Explore Our Custom Supplement Contract Manufacturing Services 

Do you have an idea for a revolutionary weight management supplement? Do you want to manufacture customized vegan, organic, allergen-friendly, kosher, or halal supplements for your customers? Or do you simply want to respond to the market trends and meet your customers’ expectations?

No matter your goal, we have you covered. Choose from our extensive dietary supplement contract manufacturing service offerings to get direct access to our state-of-the-art facilities and create best-in-class nutritional supplements.

Supplements and vitamins on a white background. Selective focus. Medicine.

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Products Manufactured In Our Facility Are Sold at these Leading Retailers and Online Marketplaces

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The logo of GNC, featuring the letters 'GNC' in large red block capitals
Vitamin Shoppe retailer logo
Whole Foods supermarket logo
Costco Wholesale logo
HEB Supermarket logo
Walgreens logo
Walmart logo
Walmart logo
Vitaquest packaging line with white supplement bottles.

Start Your Dietary Supplement Contract Manufacturing Project Today!

Request a competitive manufacturing price quote  to learn how we can bring your supplement ideas to life. 

Quick Tips for Choosing the Right Nutritional Supplement Contract Manufacturer 

Choosing the ideal nutraceutical supplement contract manufacturer can feel overwhelming and perplexing, yet it’s undeniably the crucial first step when creating a new product for the market. A wrong decision at this initial stage can be disastrous.

Here are some quick tips to help you find the right vendor:

Understand Your Needs

Start with a clear understanding of what your supplement needs are and what you want to offer your customers (If you are uncertain, Vitaquest can help). 

Minimum Order

Check the MOQs of the contract manufacturer to ensure they align with your goals. 

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Fulfillment

Explore any add-on services – like warehousing and fulfillment solutions – the contract manufacturer may offer. 

Turnaround Times

Verify and confirm that turnaround times align with your planned timelines. 

R&D and Quality

Prioritizing the R&D expertise and quality measures of the contract manufacturer can help you ensure the quality of supplement products hitting the shelves. 

Flexibility

Flexibility is the key when innovating and developing custom supplement formulations. Be sure to seek flexibility from your contract supplement manufacturer. 

Long-Term Strategy

As a brand owner, you will not stop at a single product and will need contract manufacturing support to build and expand your product line. So, focus on long-term strategy and building lasting relationships with your contract manufacturer. 

Formulation

Developing a custom formulation is not easy. Evaluate what formulation assistance and expertise a contract manufacturer would bring to the table before working with them. 

Additional Capabilities

Go beyond just supplement manufacturing. Explore what additional capabilities and services – like particle engineering, regulatory assistance or packaging and labeling – the contract manufacturer may be able to offer. 

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Price

Although price may be a big factor, don’t forget you get what you pay for in the dietary supplement industry. The quality and safety of the product should be your largest priority. If a lower price seems too good to be true, you’ll likely receive a lower-quality supplement product.

Need Help Finding the Right Custom Supplement Manufacturer?

We have helped hundreds of brand owners make the right choice for their businesses.

 

Frequently Asked Questions:

What is a supplement contract manufacturer? 

A supplement contract manufacturer is a third-party facility that can help you manufacture dietary supplements, starting from research, custom formulation, and ingredient sourcing to manufacturing, quality control, and packaging. 

The cost of manufacturing dietary supplements depends on a variety of factors, including – but not limited to – ingredients, dosage, delivery format, and packaging. Once we have this information, our team can create a custom nutraceutical manufacturing price quote for you to review. 

Production time can vary depending on the formulations, testing requirements, and other specifications of your supplement product. Once our team understands the product you want to create, we can provide you with information about the expected lead times. 

Our facility supports smaller clients and new product launches with reasonable MOQs, but you will need to contact our team for specific MOQs for the supplement product you need. 

Our cutting-edge testing facilities offer tests for:
  • Ingredient identification
    • Positive identification of materials (FT-IR, HPTLC, FT-NIR, and compendial monograph testing)
    • DNA sequencing
    • ICP-MS
    • UPLC-MS
    • Total Nitrogen Analyzer
  • Quality assurance
  • Finished product assurance
    • Potency testing (UPLC/HPLC, ICP-MS, and other methodologies)
    • Physical testing (USP disintegration, physical appearance, dissolution, and identification)
    • Purity testing (testing for pesticides (LC/MS), heavy metals (ICP-MS), and residual solvents, along with microbiological testing)
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