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Benefits of Testosterone Supplements for Men: Key Insights and Why They Matter

The Top Benefits of Testosterone Supplements for Men and Why They Matter
Testosterone supplements remain one of the most searched and competitive categories in the market. Understanding the science and consumer demand behind them can help brands position products more effectively.

Key Takeaways

  • Men may have a decline in total T levels occur at a rate of approximately 1% per year beginning in their thirties.
  • Testosterone decline may result in increased body fat or weight gain, mood changes, cognitive issues, fatigue/low energy, and sleep disturbances.
  • Ashwagandha, shilajit, Eurycoma longifolia, Fenugreek, and vitamin D are evidence-based T support nutraceuticals
  • Avoid presenting your product as a treatment for “low T”, which is a medical condition, or making comparisons to prescription T.
  • Consider the use of alternative delivery forms for your T support supplement, such as powders or effervescent tablets.

 

Research1Wang C, Nieschlag E, Swerdloff R, Behre HM. Investigation, treatment and monitoring of late-onset hypogonadism in males: ISA, ISSAM, EAU, EAA and ASA recommendations. Eur J Endocrinol. 2008;159:507–514. indicates that testosterone (T) levels tend to gradually decline as men age. Some studies2Matsumoto AM. Andropause: Clinical Implications of the Decline in Serum Testosterone Levels With Aging in Men. Journal of Gerontology. 2002. 57A(2):M76–M99. show that total testosterone decreases by approximately 1% per year beginning in the thirties, while others report an average annual decline of 1 to 2%.3Araujo AB, Wittert GA. Endocrinology of the Aging Male. Best Pract Res Clin Endocrinol Metab. 2011 April ; 25(2): 303–319. This age-related reduction in testosterone may be associated with changes in libido, body composition, mood, cognitive function, energy levels, sleep quality, and overall vitality.4Low Testosterone (Male Hypogonadism). Cleveland Clinic. Last reviewed on 09/02/2022. Retrieved December 10, 2025 from https://my.clevelandclinic.org/health/diseases/15603-low-testosterone-male-hypogonadism?utm. 5Wallace R. Signs and Symptoms of Low Testosterone. Healthline. December 20, 2024. Retrieved December 10, 2025 from https://www.healthline.com/health/low-testosterone/warning-signs?

Given these trends, consumer interest in the potential benefits of testosterone supplements has increased significantly. This growing demand is reflected in the market, which was valued at approximately $3.7 billion in 2024 and is projected to reach $10.9 billion by 2035, growing at a compounded annual growth rate (CAGR) of 10.29%.6Global Testosterone Booster Supplements Market Size To Exceed USD 10,961.1 Million by 2035 | CAGR of 10.29% : Market Study Report. Spherical Insights. Retrieved December 10, 2025 from https://www.sphericalinsights.com/our-insights/testosterone-booster-supplements-market#:~:text=Global%20Testosterone%20Booster%20Supplements%20Market%20Insights%20Forecasts%20to%202035,maintain%20energy%20and%20hormonal%20health. This article explores the role of testosterone support supplements, or more accurately, supplements designed to support the body’s natural testosterone production, as dietary supplements do not contain testosterone itself. It also addresses regulatory challenges and provides formulation tips.

For established brand owners looking to expand their product portfolios, as well as entrepreneurs considering the development of their first dietary supplement, understanding the science, regulatory considerations, and formulation strategies behind testosterone support supplements is an important first step.

Natural Supplements to Help Increase Testosterone

The following table provides a review of the previously discussed nutraceuticals, answering the question, “What are the benefits of testosterone supplements?”

Natural Supplement Potential Benefit
Ashwagandha Increase testosterone, support weight/fat loss, support stress/anxiety, support cognitive health, support sexual health, support sleep quality.
Shilajit Increase testosterone, support sexual health.
Eurycoma longifolia Increase testosterone, support stress/anxiety, support sexual health.
Fenugreek Increase testosterone, support weight/fat loss, support stress/anxiety, support cognitive health, support sexual health.
Vitamin D Increase testosterone, support weight/fat loss, support stress/anxiety, support sleep quality.

 

6 Key Benefits of Testosterone Supplements

If a man has clinically low testosterone levels, a physician may recommend testosterone replacement therapy. However, in many cases, men experiencing changes in testosterone still fall within the normal physiological range. In these situations, a variety of nutraceutical ingredients have been studied for their ability to help support healthy testosterone levels already within normal limits.

Depending on the formulation, the benefits of taking testosterone supplements may extend beyond hormone support and include support for healthy body composition, stress response, cognitive function, sexual health, and sleep quality. In the sections that follow, we explore several of these potential benefits and the role testosterone support supplements may play in addressing them.

Supports Healthy Testosterone Levels

Nutraceuticals that support healthy testosterone levels include those that are part of Ayurvedic and Asian traditional medicine. Two such nutraceuticals are Ashwagandha7Uddin, Q., Samiulla, L., Singh, V.K. and Jamil, S.S. Phytochemical and Pharmacological Profile of Withania somnifera Dunal: A Review. JAPS 2012;2:170-5. and shilajit8Sharma, P.V. 1998. Charaka Samhita. Chowkhambha Orientalia Chikitsasthana, Varanasi, Karaprchitiya RasayanaPada, 4th Edition, Volume 2. Varanasi, U.P., India: Chowkhambha Orientlia Chikitsasthana. 9Ravindra S, Reeta M, Sanka jyoti D, Swapnali D, Rama MA. Management of Male Infertility: Ayurvedic Approach. In Res J Pharm. 2013;4(6):6-7. 10Ghosal, S. The aroma principles of Gomutra and Karpuragandha Shilajit. Indian J Indg Med 1994;11:11–14., adaptogens used in Ayurvedic medicine for thousands of years. Studies11Sachin, W. Effects of Ashwagandha Root Extract (Withania somnifera) on Muscle Strength, Size and Recovery, Testosterone, and Body Fat in Healthy Adults. Unpublished;2014:25 pgs. 12Ambiye, V.R., Langade, D., Dongre, S., Aptikar, P., Kulkarni, M. and Dongre, A. Clinical Evaluation of the Spermatogenic Activity of the Root Extract of Ashwagandha (Withania somnifera) in Oligospermic Males: A Pilot Study. Evid Based Complement Alternat Med 2013;571420:6. 13Lopresti AL, Drummond PD, Smith SJ. A Randomized, Double-Blind, Placebo-Controlled, Crossover Study Examining the Hormonal and Vitality Effects of Ashwagandha ( Withania somnifera) in Aging, Overweight Males. Am J Mens Health. Mar-Apr 2019;13(2):1557988319835985. on ashwagandha use in men have shown total testosterone (T) increases of 15-17%. Studies14Pandit S, Biswas S, Jana U, De RK, Mukhopadhyay SC, Biswas TK. Clinical evaluation of purified shilajit on testosterone levels in healthy volunteers. Research Unit, J. B. Roy State Ayurvedic Medical College and Hospital, Department of Health and Family Welfare, Government of West Bengal, Kolkata, India. Submitted for publication. 2014. 15Biswas TK, Pandit S, Mondal S, Biswas SK, Jana U, Ghosh T, Tripathi PC, Debnath PK, Auddy RG, Auddy B. Clinical evaluation of spermatogenic activity of processed Shilajit in oligospermia. Andrologia. 2010 Feb;42(1):48-56. on shilajit use in men have shown total T increases of 19-23%.

Another adaptogenic herb, Eurycoma longifolia Jack (a.k.a., Tongkat Ali) is a Southeast Asian botanical traditionally used to support male vitality.16Bhat R, Karim AA. Tongkat Ali (Eurycoma longifolia Jack): a review on its ethnobotany and pharmacological importance. Fitoterapia. 2010 Oct;81(7):669-79. 17Ramawat KG (Ed.). Herbal Drugs: Ethnomedicine to Modern Medicine. Heidelberg: Springer-Verlag;2009:76. 18Handa SS, Rakesh DD, Vasisht K. Compendium of Medicinal and Aromatic Plants – Volume II: Asia. Trieste, Italy: ICS-UNIDO; 2006:81. 19Singh R, Singh S, Jeyabalan G, Ali A. An Overview on Traditional Medicinal Plants as Aphrodisiac Agent. Journal of Pharmacognosy and Phytochemistry. 2012;1(4):43-56. 20Samuel AJ, Kalusalingam A, Chellappan DK, Gopinath R, Radhamani S, Husain HA, Muruganandham V, Promwichit P. Ethnomedical survey of plants used by the Orang Asli in Kampung Bawong, Perak, West Malaysia. J Ethnobiol Ethnomed. 2010 Feb 7;6:5. Clinical research has shown that supplementation was associated with increases in total testosterone ranging from 16 -71% in certain populations.21Talbott S, Talbott J, Negrete J, Jones M, Nichols M, and Roza J. Poster 32: Effect of Eurycoma longifoliaExtract on Anabolic Balance During Endurance Exercise. JISSN. 2006;3(1)S32. 22Talbott SM, Talbott JA, George A, Pugh M. Effect of Tongkat Ali on stress hormones and psychological mood state in moderately stressed subjects. JISSN.2013;10:28. 23LJ100® Saliva Testosterone Test. Unpublished report. HP Ingredients. Bandenton, PL. Retrieved August 24, 2012 from http://www.hpingredients.com/lj100_human_clinical_research.htm.

Fenugreek (Trigonella foenum-graecum), which has a long history of use in both Ayurvedic and traditional Asian medicine, has been shown to increase free T in men by 98%, double that of the placebo group.24Unpublished. Human clinical trial report: Effect of Testofen® on safety, anabolic activity and factors affecting exercise physiology. Gencor Nutrients, Anaheim, CA. 2008: 11pp.

And let us not forget the role of vitamin D, deficiencies and insufficiencies of which are relatively common.25Forrest KY, Stuhldreher WL. Prevalence and correlates of vitamin D deficiency in US adults. Nutr Res. 2011;31(1):48-54. 26Ginde AA, Liu MC, Camargo CA Jr. Demographic differences and trends of vitamin D insufficiency in the US population, 1988-2004. Arch Intern Med. 2009;169:626-32. Research27Pilz S, Frisch S, Koertke H, Kuhn J, Dreier J, Obermayer-Pietsch B, Wehr E, Zittermann A. Effect of vitamin D supplementation on testosterone levels in men. Horm Metab Res. 2011 Mar;43(3):223-5. indicates that supplementation with vitamin D3 in men with low baseline levels was associated with increased total testosterone concentrations.

Supports Weight/Fat Loss

These same testosterone support nutraceuticals have been shown to have benefits for weight loss/fat loss in men. For example, supplementation with ashwagandha extract has been shown to significantly reduce body fat28Sachin, W. Effects of Ashwagandha Root Extract (Withania somnifera) on Muscle Strength, Size and Recovery, Testosterone, and Body Fat in Healthy Adults. Unpublished;2014:25 pgs. as well as improve food cravings.29Choudhary D, Bhattacharyya S, Joshi K. Body Weight Management in Adults Under Chronic Stress Through Treatment With Ashwagandha Root Extract: A Double-Blind, Randomized, Placebo-Controlled Trial. J Evid Based Complementary Altern Med. 2017 Jan;22(1):96-106. doi: 10.1177/2156587216641830. Epub 2016 Apr 6. PMID: 27055824; PMCID: PMC5871210. Fenugreek extract has been shown to reduce dietary fat intake.30Chevassus H, Molinier N, Costa F, Galtier F, Renard E, Petit P. A fenugreek seed extract selectively reduces spontaneous fat consumption in healthy volunteers. Eur J Clin Pharmacol. 2009 Dec;65(12):1175-8. doi: 10.1007/s00228-009-0733-5. Epub 2009 Oct 7. PMID: 19809809. Vitamin D supplementation in individuals with vitamin D deficiency has been associated with greater reductions in body weight and fat mass compared to diet alone31Lotfi-Dizaji L, Mahboob S, Aliashrafi S, Vaghef-Mehrabany E, Ebrahimi-Mameghani M, Morovati A. Effect of vitamin D supplementation along with weight loss diet on meta-inflammation and fat mass in obese subjects with vitamin D deficiency: A double-blind placebo-controlled randomized clinical trial. Clin Endocrinol (Oxf). 2019 Jan;90(1):94-101. doi: 10.1111/cen.13861. Epub 2018 Nov 12. PMID: 30246883., and also has modestly reduced BMI and waist circumference.32Perna S. Is Vitamin D Supplementation Useful for Weight Loss Programs? A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Medicina (Kaunas). 2019 Jul 12;55(7):368. doi: 10.3390/medicina55070368. PMID: 31336940; PMCID: PMC6681300.

Supports Occasional Stress and Anxiety Management

Since adaptogens are known to have benefits with stress and anxiety, it is no surprise that men supplemented with ashwagandha had significant reductions in occasional anxiety (stress-induced) scores (P=0.04), as well as a reduction in cortisol (P < .001), the stress hormone. 33Lopresti AL, Smith SJ, Malvi H, Kodgule R. An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study. Medicine (Baltimore). 2019 Sep;98(37):e17186. 34Remenapp A, Coyle K, Orange T, et al. Effectiveness of Ashwaganda (Withania somnifera) Supplementation on Adult’s Cognition and Mood. Submitted to Journal of Ayurveda and Integrative Medicine as a short communication; 2021. Likewise, men supplementing the adaptogen E, longifolia extract, experienced at cortisol decrease of 16%35Talbott SM, Talbott JA, George A, Pugh M. Effect of Tongkat Ali on stress hormones and psychological mood state in moderately stressed subjects. J Int Soc Sports Nutr. 2013 May 26;10(1):28. doi: 10.1186/1550-2783-10-28. PMID: 23705671; PMCID: PMC3669033., and an improvement in occasional anxiety levels (stress-related).36Hausenblas HA, Conway KL, Coyle KRM, Barton E, Smith LD, Esposito M, Harvey C, Oakes D, Hooper DR. Efficacy of fenugreek seed extract on men’s psychological and physical health: a randomized placebo-controlled double-blind clinical trial. J Complement Integr Med. 2020 May 22;18(2):445-448. doi: 10.1515/jcim-2019-0101. PMID: 32441668. Although not an adaptogen vitamin D supplementation has been associated with modest improvements in cognitive function, which may indirectly support stress resilience and mental performance.37Chen WY, Cheng YC, Chiu CC, Liu HC, Huang MC, Tu YK, Kuo PH. Effects of Vitamin D Supplementation on Cognitive Outcomes: A Systematic Review and Meta-Analysis. Neuropsychol Rev. 2024 Jun;34(2):568-580. doi: 10.1007/s11065-023-09598-z. Epub 2023 Jul 7. PMID: 37418225.

Supports Cognitive Health

Since lower testosterone concentrations in men are associated with a greater likelihood of cognitive decline38Yeap BB, Flicker L. Testosterone, cognitive decline and dementia in ageing men. Rev Endocr Metab Disord. 2022 Dec;23(6):1243-1257. doi: 10.1007/s11154-022-09728-7., it makes sense that testosterone support nutraceuticals may support cognitive function. This was shown to be the case when men were supplemented with ashwagandha extract, and in turn experienced an increase in short-term and working memory, improvements in sustained attention39Xing D, Yoo C, Rasmussen CJ, et al. Acute ashwagandha supplementation improves cognitive performance. JISSN. 2020 17:67, as well as cognitive flexibility, visual memory, reaction time, and executive functioning.40Remenapp A, Coyle K, Orange T, et al. Effectiveness of Ashwaganda (Withania somnifera) Supplementation on Adult’s Cognition and Mood. Submitted to Journal of Ayurveda and Integrative Medicine as a short communication; 2021. Likewise, improvements in memory scores and quality of life were noted when men were supplemented with fenugreek extract.41Foroumandi E, Javan R, Moayed L, Fahimi H, Kheirabadi F, Neamatshahi M, Shogofteh F, Zarghi A. The effects of fenugreek seed extract supplementation in patients with Alzheimer’s disease: A randomized, double-blind, placebo-controlled trial. Phytother Res. 2023 Jan;37(1):285-294. doi: 10.1002/ptr.7612. Epub 2022 Oct 5. PMID: 36199177.

Supports Overall Sexual Health

The relationship between testosterone and sexual health is well established. As such, it isn’t really a surprise that men supplemented with ashwagandha extract experienced a significant increase in sperm count (P<0.0001) and semen volume (P< 0.0001).42Ambiye, V.R., Langade, D., Dongre, S., Aptikar, P., Kulkarni, M. and Dongre, A. Clinical Evaluation of the Spermatogenic Activity of the Root Extract of Ashwagandha (Withania somnifera) in Oligospermic Males: A Pilot Study. Evid Based Complement Alternat Med 2013;571420:6. Similarly, when men were supplemented with shilajit material, there was a significant increase in normal sperm count (P < 0.001).43Biswas TK, Pandit S, Mondal S, Biswas SK, Jana U, Ghosh T, Tripathi PC, Debnath PK, Auddy RG, Auddy B. Clinical evaluation of spermatogenic activity of processed Shilajit in oligospermia. Andrologia. 2010 Feb;42(1):48-56. In other research44Tambi MI. Nutrients and Botanicals for optimizing Men’s Health. Examining the evidence for Eurycoma longifolia longjack, the Malaysian Ginseng in men’s health. Asian Journal of Andrology. 2009;11(5 suppl):37-38. 45Tambi MIBM, Imran MK, Henkel RR. Standardised water-soluble extract of Eurycoma longifolia, Tongkat ali, as testosterone booster for managing men with late-onset hypogonadism? Andrologia. 2012;44:226–230. 46Tambi MIM, Saad JM. Water-soluble extract of Eurycoma longifolia Jack soluble extract as a potential natural energizer for healthy aging men. Specialist Reproductive Research Center, National Population & Family Development Board, Ministry of Women & Family Development, Malaysia. 2000:9 pgs., men with E. longifolia extract had improvements in sexual health scores (as much as 91%), while supplementation with fenugreek seed extract promoted sexual cognition, sexual arousal, sexual behavior, and orgasm.47Steels E, Rao A, Vitetta L. Physiological aspects of male libido enhanced by standardized Trigonella foenum-graecum extract and mineral formulation. Phytother Res. 2011; 25(9):1294-300.

Supports Sleep Quality

As with cognitive health, lower testosterone concentrations in men and reduce sleep quality.48Barrett-Connor E, Dam TT, Stone K, Harrison SL, Redline S, Orwoll E; Osteoporotic Fractures in Men Study Group. The association of testosterone levels with overall sleep quality, sleep architecture, and sleep-disordered breathing. J Clin Endocrinol Metab. 2008 Jul;93(7):2602-9. doi: 10.1210/jc.2007-2622.  Additionally, stress can have the same effect.49Zhang J, Xiang S, Li X, Tang Y, Hu Q. The impact of stress on sleep quality: a mediation analysis based on longitudinal data. Front Psychol. 2024 Oct 21;15:1431234. doi: 10.3389/fpsyg.2024.1431234. Consequently, it makes sense that some of these same nutraceuticals may help with sleep quality in men. This was shown when supplementation with ashwagandha extract resulted in a 72% increase in self-reported sleep quality (compared with 29% in the placebo group)50Deshpande A, Irani N, Balkrishnan R, Benny IR. A randomized, double blind, placebo controlled study to evaluate the effects of ashwagandha (Withania somnifera) extract on sleep quality in healthy adults. Sleep Med. 2020 Aug;72:28-36., as well as faster sleep onset, improved sleep efficiency, and favorable changes in other sleep parameters.51Langade D, Kanchi S, Salve J, Debnath K, Ambegaokar D. Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double-blind, Randomized, Placebo-controlled Study. Cureus. 2019 Sep 28;11(9):e5797. doi: 10.7759/cureus.5797. PMID: 31728244; PMCID: PMC6827862. 52Cheah KL, Norhayati MN, Husniati Yaacob L, Abdul Rahman R. Effect of Ashwagandha (Withania somnifera) extract on sleep: A systematic review and meta-analysis. PLoS One. 2021 Sep 24;16(9):e0257843. doi: 10.1371/journal.pone.0257843. PMID: 34559859; PMCID: PMC8462692. In addition, when men were supplemented with vitamin D, there was improved sleep quality, less time to fall asleep, and increased sleep duration compared with placebo.53Majid MS, Ahmad HS, Bizhan H, Hosein HZM, Mohammad A. The effect of vitamin D supplement on the score and quality of sleep in 20-50 year-old people with sleep disorders compared with control group. Nutr Neurosci. 2018 Sep;21(7):511-519. doi: 10.1080/1028415X.2017.1317395. Epub 2017 May 5. PMID: 28475473.

Regulatory Environment and Challenges

If you are considering marketing/selling a testosterone support supplement, there are some regulatory issues to consider.

First and foremost, you cannot present your product as a treatment for “low T”, which is a medical condition. Rather, you can present it as a supplement that helps support healthy T levels already in a normal range. Remember, a man can still be at the lower end of a normal range of T but experience improvements when supplementing with testosterone support nutraceuticals.

Also, you should never present a testosterone support supplement as an alternative to prescription T, or in any way compare it to prescription T. In doing so, you will have inadvertently implied that your supplement is an unapproved drug. A smart approach would be to use structure/function language such as “supports healthy testosterone levels already in a normal range”. In any case, it is best to consult with expert legal counsel in structuring your claim language.

Expert Tips for Formulating Testosterone Supplements

Testosterone supplements may be offered in different delivery forms. Certainly, capsules are the most common. Nevertheless, there are other delivery forms such as powders (stick-packs) or effervescent tablets to consider. These may hold greater appeal to younger men who tend to have more interest in such alternative delivery forms, and for whom testosterone support supplements are commonly used for purposes of supporting strength-training efforts. However, since consumers will be able to taste the bitter notes associated with some of the testosterone support nutraceuticals when using these alternative delivery forms, it is best to include bitter masking agents and strong flavors such as grape or mixed berries.

Another formulation tip is to utilize multiple nutraceuticals with supportive science for your new supplement. Not only will this give the formulation greater appeal, but, assuming you utilize clinically relevant doses of each nutraceutical, consumers are more likely to experience better results when taking your product, which bodes well for repeat sales. Furthermore, if, in addition to testosterone support, you intend to focus on other specific claim areas in your supplement (e.g., healthy body composition, stress response, cognitive function, sexual health, sleep quality), you might also consider the addition of complementary nutraceuticals to support these functions.

Wrapping up the Discussion on the Benefits of Testosterone Supplements for Men’s Health

Age-related declines in testosterone are a normal part of male physiology, with research suggesting total testosterone levels may decrease by approximately 1% per year beginning in the thirties. For many men, these changes can be associated with shifts in body composition, energy levels, mood, cognitive performance, sleep quality, and sexual health.

As outlined in this article, a growing body of human research supports the role of specific nutraceutical ingredients such as ashwagandha, shilajit, Eurycoma longifolia, fenugreek, and vitamin D in helping support healthy testosterone levels already within the normal range. These findings help explain the increasing interest in the benefits of testosterone supplements, including broader support for weight management, stress response, cognition, sleep quality, and overall vitality.

For brand owners considering the development of a testosterone support product, selecting the right dietary supplement manufacturing partner is critical. Experience with testosterone-focused formulations, deep regulatory expertise, strong sustainability practices, and third-party GMP certification, preferably from NSF, should all factor into your decision. Vitaquest brings more than 45 years of contract development and manufacturing experience to this category and supports both emerging and established brands throughout every step of the process.

If you’re ready to capitalize on growing consumer demand for high-quality testosterone support supplements, call 800-526-9095 to speak with one of our knowledgeable sales executives or request a nutraceutical manufacturing price quote today if you’ve already finalized your project requirements!

 

References

  • 1
    Wang C, Nieschlag E, Swerdloff R, Behre HM. Investigation, treatment and monitoring of late-onset hypogonadism in males: ISA, ISSAM, EAU, EAA and ASA recommendations. Eur J Endocrinol. 2008;159:507–514.
  • 2
    Matsumoto AM. Andropause: Clinical Implications of the Decline in Serum Testosterone Levels With Aging in Men. Journal of Gerontology. 2002. 57A(2):M76–M99.
  • 3
    Araujo AB, Wittert GA. Endocrinology of the Aging Male. Best Pract Res Clin Endocrinol Metab. 2011 April ; 25(2): 303–319.
  • 4
    Low Testosterone (Male Hypogonadism). Cleveland Clinic. Last reviewed on 09/02/2022. Retrieved December 10, 2025 from https://my.clevelandclinic.org/health/diseases/15603-low-testosterone-male-hypogonadism?utm.
  • 5
    Wallace R. Signs and Symptoms of Low Testosterone. Healthline. December 20, 2024. Retrieved December 10, 2025 from https://www.healthline.com/health/low-testosterone/warning-signs?
  • 6
    Global Testosterone Booster Supplements Market Size To Exceed USD 10,961.1 Million by 2035 | CAGR of 10.29% : Market Study Report. Spherical Insights. Retrieved December 10, 2025 from https://www.sphericalinsights.com/our-insights/testosterone-booster-supplements-market#:~:text=Global%20Testosterone%20Booster%20Supplements%20Market%20Insights%20Forecasts%20to%202035,maintain%20energy%20and%20hormonal%20health.
  • 7
    Uddin, Q., Samiulla, L., Singh, V.K. and Jamil, S.S. Phytochemical and Pharmacological Profile of Withania somnifera Dunal: A Review. JAPS 2012;2:170-5.
  • 8
    Sharma, P.V. 1998. Charaka Samhita. Chowkhambha Orientalia Chikitsasthana, Varanasi, Karaprchitiya RasayanaPada, 4th Edition, Volume 2. Varanasi, U.P., India: Chowkhambha Orientlia Chikitsasthana.
  • 9
    Ravindra S, Reeta M, Sanka jyoti D, Swapnali D, Rama MA. Management of Male Infertility: Ayurvedic Approach. In Res J Pharm. 2013;4(6):6-7.
  • 10
    Ghosal, S. The aroma principles of Gomutra and Karpuragandha Shilajit. Indian J Indg Med 1994;11:11–14.
  • 11
    Sachin, W. Effects of Ashwagandha Root Extract (Withania somnifera) on Muscle Strength, Size and Recovery, Testosterone, and Body Fat in Healthy Adults. Unpublished;2014:25 pgs.
  • 12
    Ambiye, V.R., Langade, D., Dongre, S., Aptikar, P., Kulkarni, M. and Dongre, A. Clinical Evaluation of the Spermatogenic Activity of the Root Extract of Ashwagandha (Withania somnifera) in Oligospermic Males: A Pilot Study. Evid Based Complement Alternat Med 2013;571420:6.
  • 13
    Lopresti AL, Drummond PD, Smith SJ. A Randomized, Double-Blind, Placebo-Controlled, Crossover Study Examining the Hormonal and Vitality Effects of Ashwagandha ( Withania somnifera) in Aging, Overweight Males. Am J Mens Health. Mar-Apr 2019;13(2):1557988319835985.
  • 14
    Pandit S, Biswas S, Jana U, De RK, Mukhopadhyay SC, Biswas TK. Clinical evaluation of purified shilajit on testosterone levels in healthy volunteers. Research Unit, J. B. Roy State Ayurvedic Medical College and Hospital, Department of Health and Family Welfare, Government of West Bengal, Kolkata, India. Submitted for publication. 2014.
  • 15
    Biswas TK, Pandit S, Mondal S, Biswas SK, Jana U, Ghosh T, Tripathi PC, Debnath PK, Auddy RG, Auddy B. Clinical evaluation of spermatogenic activity of processed Shilajit in oligospermia. Andrologia. 2010 Feb;42(1):48-56.
  • 16
    Bhat R, Karim AA. Tongkat Ali (Eurycoma longifolia Jack): a review on its ethnobotany and pharmacological importance. Fitoterapia. 2010 Oct;81(7):669-79.
  • 17
    Ramawat KG (Ed.). Herbal Drugs: Ethnomedicine to Modern Medicine. Heidelberg: Springer-Verlag;2009:76.
  • 18
    Handa SS, Rakesh DD, Vasisht K. Compendium of Medicinal and Aromatic Plants – Volume II: Asia. Trieste, Italy: ICS-UNIDO; 2006:81.
  • 19
    Singh R, Singh S, Jeyabalan G, Ali A. An Overview on Traditional Medicinal Plants as Aphrodisiac Agent. Journal of Pharmacognosy and Phytochemistry. 2012;1(4):43-56.
  • 20
    Samuel AJ, Kalusalingam A, Chellappan DK, Gopinath R, Radhamani S, Husain HA, Muruganandham V, Promwichit P. Ethnomedical survey of plants used by the Orang Asli in Kampung Bawong, Perak, West Malaysia. J Ethnobiol Ethnomed. 2010 Feb 7;6:5.
  • 21
    Talbott S, Talbott J, Negrete J, Jones M, Nichols M, and Roza J. Poster 32: Effect of Eurycoma longifoliaExtract on Anabolic Balance During Endurance Exercise. JISSN. 2006;3(1)S32.
  • 22
    Talbott SM, Talbott JA, George A, Pugh M. Effect of Tongkat Ali on stress hormones and psychological mood state in moderately stressed subjects. JISSN.2013;10:28.
  • 23
    LJ100® Saliva Testosterone Test. Unpublished report. HP Ingredients. Bandenton, PL. Retrieved August 24, 2012 from http://www.hpingredients.com/lj100_human_clinical_research.htm.
  • 24
    Unpublished. Human clinical trial report: Effect of Testofen® on safety, anabolic activity and factors affecting exercise physiology. Gencor Nutrients, Anaheim, CA. 2008: 11pp.
  • 25
    Forrest KY, Stuhldreher WL. Prevalence and correlates of vitamin D deficiency in US adults. Nutr Res. 2011;31(1):48-54.
  • 26
    Ginde AA, Liu MC, Camargo CA Jr. Demographic differences and trends of vitamin D insufficiency in the US population, 1988-2004. Arch Intern Med. 2009;169:626-32.
  • 27
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Michael Anthonavage, Vice President of Innovation for Vitaquest International
Michael
Anthonavage
VP Innovation

Michael Anthonavage serves as the VP of Innovation at Vitaquest, dedicated to expanding the supplement market footprint and ensuring a competitive edge. With expertise in bringing new technologies to the personal care industry, championing patents for natural skincare, and contributing to skin biology research, he’s an educator and a member of the scientific advisory board for the NYC Society of Cosmetic Chemists.

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