The global dietary supplement market is projected to reach $203.42 billion in 2025 and nearly double to $402.2 billion by 2034, growing at a compounded annual growth rate (CAGR) of 7.87%.1Dietary Supplements Market Size Worth USD 402.20 Billion by 2034. GlobeNewsWire. April 14, 2025. Retrieved June 16, 2025 from https://www.globenewswire.com/news-release/2025/04/14/3061113/0/en/Dietary-Supplements-Market-Size-Worth-USD-402-20-Billion-by-2034.html.
As the market continues to expand, not all product categories will grow equally, especially with seasonal demand shaping purchasing behavior. Understanding winter supplements trends is essential for brand owners preparing to meet evolving consumer needs during colder months.
This article explores the most important supplement market trends to watch for during the winter of 2026, and how they will influence product development, marketing, and retail strategy in the year ahead.
Supplement Categories in Demand for Winter 2026
Key winter supplement trends for 2026 highlight growing consumer interest across several high-demand categories. These include:
- Vegan supplements, driven by plant-based lifestyles and clean-label preferences
- Immune and respiratory support, as consumers prepare for seasonal health challenges
- Beauty-from-within products, targeting skin hydration and radiance during colder months
- Stress and mood support, reflecting continued demand for emotional well-being
In addition to these categories, convenient supplement formats, such as capsules, tablets, and powders packaged in stick packs, remain a priority. We also expect to see increased focus on formulation innovation that enhances efficacy, stability, and user experience. These supplement market trends offer strategic opportunities for brand differentiation and revenue growth this winter.
Vegan Supplements for Winter
The global vegan supplements market has experienced significant growth, reaching approximately $9.1 billion in 2024, with projections hitting $17.7 billion by 2034 at a CAGR of 6.9%.2Vegan Supplements Market Projected to Reach USD 17.7 Billion by 2034, Fueled by Growing Demand for Plant-Based and Sustainable Products: Future Market Insights, Inc. Yahoo!Finance. December 16, 2024. Retrieved June 16, 2025 from https://finance.yahoo.com/news/vegan-supplements-market-projected-reach-134500299.html. Consumers continue to favor supplements made with natural, plant-based ingredients, viewing them as gentler on the body, easier to digest, and aligned with environmental values.
As demand rises, especially during colder months, many turn to vegan-friendly options that feature some of the best vitamins for winter, including vitamin D, vitamin C, and B-complex vitamins. These nutrients have been shown to support a healthy immune system, energy metabolism, and overall well-being, making them ideal choices for plant-based formulations targeting winter health needs.
Vegan Vitamin D
Among all winter vitamins, vitamin D is arguably the most critical. During the colder months, reduced sunlight exposure due to shorter days and limited time outdoors significantly decreases the body’s natural production of vitamin D. This makes vitamin D during winter essential for maintaining immune health, mood balance, and bone support.
Most commercially available vitamin D3 is derived from lanolin, a byproduct of sheep’s wool, which undergoes chemical processing to become cholecalciferol. While effective, this form is neither vegan nor considered natural by plant-based standards.
A true vegan alternative is sourced from Cladonia rangiferina (reindeer lichen), a wildcrafted plant found in alpine regions. This plant-based D3 is available in both powder and oil formats, with conventional and organic options, making it a preferred solution for those seeking clean-label, ethical vitamin D supplementation during the winter season.
Vegan Protein Powders
Protein is essential year-round, but it plays an important role during the winter months by supporting immune function through antibody formation and helping the body maintain temperature.3Protein during the winter months. OA online. December 27, 2023. Retrieved June 16, 2025 from https://www.oaoa.com/people/food/protein-during-the-winter-months/#google_vignette Vegan and plant-based proteins continue to gain popularity, with the market projected to grow from $16.05 billion in 2024 to $20.43 billion by 2029, at a CAGR of 4.94%.4Plant Protein Market SIZE & SHARE ANALYSIS – GROWTH TRENDS & FORECASTS UP TO 2029. Mordor Intelligence. Retrieved October 18, 2024 from https://www.mordorintelligence.com/industry-reports/global-plant-protein-market.
Common sources of vegan protein include pea, rice, and hemp:
- Pea protein is highly digestible and has been shown to support thermogenesis5Claessens M, Calame W, Siemensma AD, Saris WH, van Baak MA. The thermogenic and metabolic effects of protein hydrolysate with or without a carbohydrate load in healthy male subjects. Metabolism. 2007 Aug;56(8):1051-9., promote satiety6Smith CE, Mollard RC, Luhovyy BL, Anderson GH. The effect of yellow pea protein and fibre on short-term food intake, subjective appetite and glycaemic response in healthy young men. Br J Nutr. 2012 Aug;108 Suppl 1:S74-80., maintain healthy blood pressure levels already within normal ranges7Li H, Prairie N, Udenigwe CC, Adebiyi AP, Tappia PS, Aukema HM, Jones PJ, Aluko RE. Blood pressure lowering effect of a pea protein hydrolysate in hypertensive rats and humans. J Agric Food Chem. 2011 Sep 28;59(18):9854-60., and promote muscle growth.8Babault N, Païzis C, Deley G. et al. Pea proteins oral supplementation promotes muscle thickness gains during resistance training: a double-blind, randomized, Placebo-controlled clinical trial vs. Whey protein. J Int Soc Sports Nutr. 2015; 12:3. https://doi.org/10.1186/s12970-014-0064-5.
- Rice protein is generally considered to be hypoallergenic9Michelet M, Schluckebier D, Petit LM, Caubet JC. Food protein-induced enterocolitis syndrome – a review of the literature with focus on clinical management. J Asthma Allergy. 2017 Jun 27;10:197-207. and has been shown to support gains in lean body mass and reductions in fat mass, with effects comparable to whey protein isolate.10Joy JM, Lowery RP, Wilson JM, et al. The effects of 8 weeks of whey or rice protein supplementation on body composition and exercise performance. Nutr J. 2013; 12: 86. 11Kalman D, Escalante A. P34 The body composition effects of extra protein in elite mixed martial artists undergoing frequent training over a six-week period. JISSN. 2017;14(Suppl 2):31.
- Hemp protein is derived from the cannabis plant, but doesn’t contain any THC, the psychoactive compound found in marijuana. It does, however, help maintain healthy blood pressure levels already within normal ranges12Samsamikor M, Mackay DS, Mollard RC, Alashi AM, Aluko RE. Hemp seed protein and its hydrolysate compared with casein protein consumption in adults with hypertension: a double-blind crossover study. Am J Clin Nutr. 2024;120(1):56-65. doi:10.1016/j.ajcnut.2024.05.001. and provides antioxidant protection against oxidative stress.13Zhang J, Griffin J, Li Y, Wang D, Wang W. Antioxidant Properties of Hemp Proteins: From Functional Food to Phytotherapy and Beyond. Molecules. 2022 Nov 16;27(22):7924. doi: 10.3390/molecules27227924. PMID: 36432024; PMCID: PMC9693028.
Vegan Collagen
Winter temperatures often cause dry skin, increasing demand for collagen supplements that support skin hydration and a more youthful appearance. Collagen also plays a key role in joint health, contributing to its popularity. The global market is projected to grow from $9.9 billion in 2024 to $18.7 billion by 2030.14Collagen Market Size, Share & Trends Analysis Report By Product (Gelatin, Hydrolyzed Collagen), By Source (Bovine, Porcine), By Application (Food & Beverages, Healthcare), By Region, And Segment Forecasts, 2025 – 2030. Grand View Research. Retrieved June 16, 2025 from https://www.grandviewresearch.com/industry-analysis/collagen-market#:~:text=The%20global%20collagen%20market%20size,11.3%25%20from%202025%20to%202030.
However, traditional collagen is sourced from animals such as cattle, pigs, and fish, making it unsuitable for vegan and vegetarian consumers. Fortunately, vegan-friendly alternatives are now available. While often marketed as “vegan collagen,” these products do not contain actual collagen, as collagen only occurs in animal tissue.
Instead, they are formulated using vegan-sourced amino acids that closely match the amino acid profile of animal-derived collagen, up to 98% similarity to human collagen. Clinical research has shown that 1.5 grams per day can significantly improve skin hydration, elasticity, and reduce fine lines within four weeks, with 5 grams per day yielding even more noticeable results.15Yung-Kai Lin, Chia-Hua Liang, Yung-Hsiang Lin, Tai-Wen Lin, Josué Jiménez Vázquez, Anthony van Campen, Chi-Fu Chiang. Oral supplementation of vegan collagen biomimetic has beneficial effects on human skin physiology: A double-blind, placebo-controlled study. Journal of Functional Foods. 2024; 112: 105955. https://doi.org/10.1016/j.jff.2023.105955.
Winter Immune and Respiratory Support
Fall and winter often bring a rise in respiratory illnesses, including colds and the flu16Huang D, Taha MS, Nocera AL, Workman AD, Amiji MM, Bleier BS. Cold exposure impairs extracellular vesicle swarm-mediated nasal antiviral immunity. J Allergy Clin Immunol. 2023;151(2):509-525.e8. doi:10.1016/j.jaci.2022.09.037, making immune health a top priority for many consumers. As a result, sales of immune-support supplements typically surge during these seasons.17Cold And Flu Supplements Market Size, Share & Trends Analysis Report By Product (Herbal Extracts, Natural Molecules), By Distribution Channel (Pharmacies & Drug Stores, Online), And Segment Forecasts, 2023 – 2030. Grand View Research. Retrieved June 16, 2025 from https://www.grandviewresearch.com/industry-analysis/cold-flu-supplements-market#:~:text=*%20How%20big%20is%20the%20cold%20and,preventing%20and%20treating%20cold%20and%20flu%20symptom.
To help strengthen the body’s defenses, it’s important to focus on some of the best vitamins for winter, in addition to vitamin D, which we’ve already covered. These key nutrients can play a vital role in supporting healthy immune and respiratory function during the colder months.
Vitamin C
Vitamin C is a staple in winter immune support and has been shown to play a vital role in several immune functions, including antimicrobial activity, natural killer cell function, and white blood cell (lymphocyte) proliferation.18Khassaf M, McArdle A, Esanu C, Vasilaki A, McArdle F, Griffiths RD, Brodie DA, Jackson MJ. Effect of vitamin C supplements on antioxidant defence and stress proteins in human lymphocytes and skeletal muscle. J Physiol. 2003 Jun 1;549(Pt 2):645-52.
Given its widespread use, however, standing out in the crowded vitamin C market can be challenging, even with enhanced forms like liposomal vitamin C, which offer improved bioavailability.19Bruno G. Validation and bioavailability of liposomal technology for nutraceuticals. Vitamin Retailer. March 2023: 41.3. While using a high-quality form is still recommended, combining vitamin C with other well-researched immune-support ingredients can provide a more comprehensive formula and stronger market appeal.
Effective pairings include ingredients such as zinc, elderberry, echinacea, and NAC, all of which contribute to immune resilience. Popular delivery formats for vitamin C include chewable tablets, fast melt tablets, traditional tablets, and capsules, offering both convenience and consumer familiarity.
Zinc
Zinc is essential to immune health20Food and Nutrition Board, Institute of Medicine. Zinc. Dietary reference intakes for vitamin A, vitamin K, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium, and zinc. Washington, D.C.: National Academy Press; 2001:442-501., influencing a wide range of immune responses, from lymphocyte gene regulation to maintaining the skin barrier21Food and Nutrition Board, Institute of Medicine. Zinc. Dietary reference intakes for vitamin A, vitamin K, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium, and zinc. Washington, D.C.: National Academy Press; 2001:442-501. and reducing oxidative stress markers.22Prasad AS. Zinc in human health: effect of zinc on immune cells. Mol Med 2008; 14(5-6): 353-7. It is also vital for the development and function of key immune cells, including neutrophils and natural killer cells.23Shankar AH, Prasad AS. Zinc and immune function: the biological basis of altered resistance to infection. Am J Clin Nutr. 1998 Aug;68(2 Suppl):447S-463S.
As with vitamin C, zinc is most effective during winter when included in combination formulas alongside other immune-support ingredients such as vitamin C and select botanicals. Effective delivery formats include lozenges, chewable and fast melt tablets, traditional tablets, and capsules.
Elderberry
Elderberry is a clinically studied herb known to support antibody production and enhance immune response. In clinical settings, elderberry has been shown to significantly improve immune function within 48 hours.24Zakay-Rones Z1, Varsano N, Zlotnik M, Manor O, Regev L, Schlesinger M, Mumcuoglu M. Inhibition of several strains of influenza virus in vitro and reduction of symptoms by an elderberry extract (Sambucus nigra L.) during an outbreak of influenza B Panama. J Altern Complement Med. 1995 Winter;1(4):361-9. 25Kong F. Pilot Clinical Study on a Proprietary Elderberry Extract: Efficacy in Addressing Influenza Symptoms, Online J Pharmacol Pharmacokin 5:32‐43, 2009. 26Kong F-K. Pilot Clinical Study on a Proprietary Elderberry Extract: Efficacy in Addressing Influenza Symptoms, Online J Pharmacol Pharmacokin. 2009; 5:32‐43.
It is well-suited for wintertime immune formulas. Common delivery formats for elderberry supplements include lozenges, chewable, and fast-melt tablets for ease of use and rapid absorption.
Echinacea Blends
Echinacea is the granddaddy of all immune-enhancing herbs. It supports the immune system through the activation of white blood cells (lymphocytes and macrophages),27See DM, Broumand N, Sahl L, Tilles JG. In vitro effects of echinacea and ginseng on natural killer and antibody-dependent cell cytotoxicity in healthy subjects and chronic fatigue syndrome or acquired immunodeficiency syndrome patients. Immunpharmacol 1997;35:229–35. and by increasing the number of T cells.28Zwickey H, Brush J, Iacullo CM, Connelly E, Gregory WL, Soumyanath A, Buresh R. The effect of Echinacea purpurea, Astragalus membranaceus and Glycyrrhiza glabra on CD25 expression in humans: a pilot study. Phytother Res. 2007 Nov;21(11):1109-12. 29Brush J, Mendenhall E, Guggenheim A, Chan T, Connelly E, Soumyanath A, Buresh R, Barrett R, Zwickey H. The effect of Echinacea purpurea, Astragalus membranaceus and Glycyrrhiza glabra on CD69 expression and immune cell activation in humans. Phytother Res. 2006 Aug;20(8):687-95.
The two most popular and well-researched species of Echinacea are E. purpurea (aerial parts) and E. angustifolia (aerial parts and root). The two most well-researched species are Echinacea purpurea (aerial parts) and Echinacea angustifolia (aerial parts and root). Brands may choose to formulate with either species or combine both for a broader phytochemical profile.
Common and effective delivery forms for echinacea include lozenges, chewable and fast-melt tablets, traditional tablets, and capsules.
NAC
N-acetylcysteine (NAC) helps replenish glutathione and reduce damage caused by free radicals/ROS.30Kelly GS. Clinical applications of N-acetylcysteine. Altern Med Rev 1998;3:114-27.
Human clinical research also shows that NAC supplementation was effective in promoting cell-mediated immunity when used for six months.31De Flora S, Grassi C, Carati L. Attenuation of influenza-like symptomatology and improvement of cell-mediated immunity with long-term N-acetylcysteine treatment. Eur Respir J 1997;10:1535-41. 32De Flora S, Grassi C, Carati L. Attenuation of influenza-like symptomatology and improvement of cell-mediated immunity with long-term N-acetylcysteine treatment. Eur Respir J 1997;10:1535-41.
Because NAC is a sulfur-containing compound with a strong taste and odor, the most suitable delivery formats are capsules and tablets, which offer both convenience and improved consumer compliance.
Beauty From Within
The beauty from within category includes nutraceuticals that support the health and appearance of skin, hair, and nails. During the winter months, dry air and colder temperatures often lead to increased skin and hair concerns, driving seasonal demand for these supplements.
The global beauty from within market is projected to grow steadily, with an estimated value of $3.96 billion in 2025 and a forecasted increase to $5.76 billion by 2030, reflecting a CAGR of 7.8%. This continued growth highlights consumer interest in holistic beauty solutions that work from the inside out.
Listen to this podcast featuring our VP of Innovation, Michael Anthonavage, and Dr. Gene Bruno as they explore the science, innovation, and consumer demand fueling the beauty-from-within category.
Collagen Supplements
Collagen supplements, especially collagen peptides, have been shown33Proksch E, Schunck M, Zague V, Segger D, Degwert J, Oesser S. Oral intake of specific bioactive collagen peptides reduces skin wrinkles and increases dermal matrix synthesis. Skin Pharmacol Physiol. 2014;27(3):113-9. to support and stimulate the body’s own collagen production, increasing pro-collagen production by 65%, as well as production of the critical skin protein, elastin, by 18%.
Likewise, studies34Proksch E, Schunck M, Zague V, Segger D, Degwert J, Oesser S. Oral intake of specific bioactive collagen peptides reduces skin wrinkles and increases dermal matrix synthesis. Skin Pharmacol Physiol. 2014;27(3):113-9. 35Proksch E, Segger D, Degwert J, Schunck M, Zague V, Oesser S. Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: a double-blind, placebo-controlled study. Skin Pharmacol Physiol. 2014;27(1):47-55. 36Proksch E, Schunck M, Zague V, Segger D, Degwert J, Oesser S. Oral intake of specific bioactive collagen peptides reduces skin wrinkles and increases dermal matrix synthesis. Skin Pharmacol Physiol. 2014;27(3):113-9. 37Oesser S. The oral intake of specific Bioactive Collagen Peptides has a positive effect on hair thickness. Nutrafoods (2020) 1:134-138. has demonstrated that it significantly reduced wrinkles, improved skin elasticity and moisture, reduced cellulite, and increased hair thickness.
Powder is generally the best delivery format for collagen to accommodate the 2.5 to 5 g dose.
Hyaluronic Acid
Hyaluronic acid is a naturally occurring substance found in human skin38Chen WY, Abatangelo G . Functions of hyaluronan in wound repair. Wound Repair Regen. 1999;7(2):79–89. that plays a key role in maintaining hydration by binding with water.39Tammi R, Ripellino JA, Margolis RU, Maibach HI, Tammi M. Hyaluronate accumulation in human epidermis treated with retinoic acid in skin organ culture. J Invest Dermatol. 1989;92(3):326–32. 40Tuhkanen AL, Tammi M, Pelttari A, Agren UM, Tammi R. Ultrastructural analysis of human epidermal CD44 reveals preferential distribution on plasma membrane domains facing the hyaluronan-rich matrix pouches. J Histochem Cytochem. 1998;46 (2):241–8. However, skin levels of hyaluronic acid decline with age41Papakonstantinou E, Roth M, Karakiulakis G. Hyaluronic acid: A key molecule in skin aging. Dermatoendocrinol. 2012 Jul 1; 4(3): 253–258., contributing to dryness and the appearance of fine lines.42Hsu TF, Su ZR, Hsieh YH, Wang MF, Oe M, Matsuoka R, Masuda Y. Oral Hyaluronan Relieves Wrinkles and Improves Dry Skin: A 12-Week Double-Blinded, Placebo-Controlled Study. Nutrients. 2021 Jun 28;13(7):2220. doi: 10.3390/nu13072220. PMID: 34203487; PMCID: PMC8308347.
Fortunately, oral supplementation with hyaluronic acid has been clinically shown to increase skin moisture content and help reduce the appearance of wrinkles, making it a valuable ingredient in beauty-from-within formulations.
Effective delivery formats include lozenges, chewable tablets, fast melt tablets, traditional tablets, and capsules because they offer consumers flexibility and convenience.
Biotin
If you have a biotin deficiency resulting in hair loss43Zempleni J, et al. Expert Rev Endocrinol Metab 2008;3(6):715–724., biotin supplementation may help. However, in otherwise healthy individuals, biotin alone is unlikely to significantly impact hair growth44Soleymani T, et al. J Drugs Dermatol. 2017 May 1;16(5):496-500., although it may provide added value when combined with keratin.45Beer C, Wood S, Veghte RH. A Clinical Trial to Investigate the Effect of Cynatine HNS on Hair and Nail Parameters.The Scientific World Journal. 2014; 2014, Article ID 641723:6 pgs.
Research also suggests that biotin may help reduce fingernail splitting and improve nail thickness46Floersheim GL. [Treatment of brittle fingernails with biotin]. Z Hautkr. 1989;64(1):41-48., making it a popular ingredient in nail health supplement formulations.
Ideal delivery forms include lozenges, chewables, fast melts, capsules, and tablets, offering consumers a range of convenient options.
Spermidine
Spermidine is one of three polyamine compounds found in foods and produced in our bodies. Research has demonstrated that spermidine alone47Rinaldi F, Sorbellini E, Bezzola P, Marchioretto DI. Biogenina® based food supplement: hair growth enhancer. NutraFood. 2003;2:1-7., or in combination with other nutraceuticals48Rinaldi F, Sorbellini E, Bezzola P, Marchioretto DI. Biogenina® based food supplement: hair growth enhancer. NutraFood. 2003;2:1-7. 49Rinaldi F, Marzani B, Pinto D, Ramot Y. A spermidine-based nutritional supplement prolongs the anagen phase of hair follicles in humans: a randomized, placebo-controlled, double-blind study. Dermatol Pract Concept. 2017 Oct 31;7(4):17-21., helps promote hair growth, reduce hair loss, and increase hair thickness.
In a subsequent study50Bruno G, et al. The Impact of 6 Weeks of Supplementation with Miricell™ Rice Germ Extract on Hair & Nail Health – A Clinical Study Report. Unpublished; 2025., a spermidine-rich rice germ extract, had the same effects on hair but also improved nail growth and increased nail thickness.
Effective delivery forms for spermidine include lozenges, chewables, fast melts, capsules, and tablets, providing flexibility for supplement formulation and consumer preference.
Vitamin E
Vitamin E, a powerful antioxidant, plays an important role in protecting the skin from oxidative stress and supporting overall skin health. However, like vitamin C, it is most effective when used in combination with other nutraceuticals.
For example51Heinrich U, Tronnier H, Stahl W, Béjot M, Maurette JM. Antioxidant supplements improve parameters related to skin structure in humans. Skin Pharmacol Physiol 2006;19(4):224-31., a blend of vitamin E, lycopene, beta-carotene, and selenium has been shown to reduce skin scaling and roughness while increasing skin density and thickness, both indicators of healthier, more youthful-looking skin. Additionally, a combination of vitamin E and vitamin C has been demonstrated to help prevent UV-induced skin redness.52Pannelli F, La Rosa F, Saltalamacchia G, et al. Tobacco smoking, coffee, cocoa, and tea consumption in relation to mortality from urinary bladder cancer in Italy. Eur J Epidemiol 1989;5:392-7. 53Fuchs J, Kern H. Modulation of UV-light-induced skin inflammation by D-alpha-tocopherol and L-ascorbic acid: a clinical study using solar simulated radiation. Free Radic Biol Med 1998;25:1006-12.
Common delivery forms for vitamin E include lozenges, chewable and fast melt tablets, traditional tablets, and capsules, making it easy to incorporate into beauty-from-within formulations.
Stress & Mood Support
The winter season, particularly around the holidays, is commonly associated with increased stress and shifts in mood54Holiday Stress and the Brain. Harvard Medical School. Retrieved June 17, 2025 from https://hms.harvard.edu/news-events/publications-archive/brain/holiday-stress-brain., often referred to as the “winter blues.” As a result, interest in stress and mood support supplements typically rises during this time of year.
Adaptogens are among the most sought-after solutions, known for their ability to help the body adapt to physical and emotional stress. Other beneficial supplements to take during winter months include L-theanine, magnesium, vitamin D, and melatonin, each of which supports relaxation, mood balance, and restful sleep. These ingredients can be formulated individually or as part of comprehensive stress support blends tailored to seasonal needs.
Adaptogens for Winter
Adaptogens are substances, typically herbs, that help the body achieve balance, or homeostasis, especially during times of physical or emotional stress. While they may not exert strong direct biological effects, they are valued for their ability to support overall resilience and well-being.
Adaptogens are particularly useful in stress and mood support formulations, especially during the winter season. Among the most well-researched adaptogens are ashwagandha and Rhodiola, both of which have demonstrated effectiveness in promoting mental clarity, energy balance, and emotional stability.
These ingredients are also commonly used in supplements for winter tiredness, helping to counteract seasonal fatigue and improve daily functioning.
Ashwagandha
Ashwagandha (Withania somnifera) has been used in Ayurvedic medicine55Anonymous. Monograph. Withania somnifera. Altern Med Rev 2004;9:211-4. for over 3,000 years. As an adaptogen, it helps the body adapt to stress by normalizing physiological functions under strain, resulting in broad-ranging benefits.56Provino R. The role of adaptogens in stress management. Aust J Med Herbal. 2010;22:41-9
Ashwagandha has been traditionally used to reduce stress and enhance well-being. Likewise, scientific research also supports these uses. In randomized controlled trials (RCT)57Lopresti AL, Smith SJ, Malvi H, Kodgule R. An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study. Medicine (Baltimore). 2019 Sep;98(37):e17186. ashwagandha extract was found to significantly reduce stress and anxiety levels and lower cortisol, the body’s primary stress hormone.
Rhodiola Rosea
Rhodiola rosea (commonly referred to as Rhodiola or Arctic Root) has been used for centuries in the traditional medicine of Russia, Scandinavia, and other countries to increase physical endurance, work productivity, longevity, resistance to high altitude sickness, and to help reduce fatigue and moodiness and promoting sexual health.58Brown RP, Gerbarg PL, Ramazanov Z. Rhodiola rosea: A Phytomedicinal Overview. HerbalGram 2002; 56:40-52.
Modern scientific studies in cell cultures, animals, and humans have revealed anti-fatigue, anti-stress, anti-hypoxia (protection against damaging effects of oxygen deprivation), antioxidant, immune-enhancing, and sexual stimulating effects.59Saratikov AS, Krasnov EA. Rhodiola rosea is a valuable medicinal plant (Golden Root). Tomsk, Russia: Tomsk State University; 1987. 60Darbinyan V, Kteyan A, Panossian A, Gabrielian E, Wikman G, Wagner H. Rhodiola rosea in stress-induced fatigue—a double blind crossover study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental performance of healthy physicians during night duty. Phytomedicine 2000; 7(5):365-71. 61Saratikov AS. Golden Root (Rhodiola rosea). Russia: Tomsk; 1974. 62Spasov AA, Wikman GK, Mandrikov VB, Mironova IA, Neumoin VV. A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the fatigue of students caused by stress during an examination period with a repeated low-dose regimen. Phytomedicine 2000; 7(2):85-9. 63Spasov AA, Mandrikov VB, Mironova IA. The effect of the preparation rodiosin on the psychophysiological and physical adaptation of students to an academic load. Eksp Klin Farmakol 2000; 63(1):76-8. 64Furmanowa M, Oledzka H, Michalska M, Sokolnicka I, Radomska D. Chapter XXIII Rhodiola rosea L. (Roseroot): in vitro regeneration and the biological activity of roots. Biotechnology in agriculture and forestry, Vol. 33. Medicinal and aromatic plants VIII (ed. by YPS Bajaj). Berlin Heidelberg: Springer-Verlag; 1995 p. 412-26. Notably, Rhodiola has been shown to enhance physical performance and significantly reduce recovery time between bouts of high-intensity exercise, making it a standout among adaptogenic herbs.65Saratikov AS, Krasnov EA. Chapter III: Stimulative properties of Rhodiola rosea. in: Saratikov AS, Krasnov EA. Rhodiola rosea is a valuable medicinal plant (Golden Root). Tomsk, Russia: Tomsk State University; 1987 p. 69-90.
L-Theanine
L-theanine is a neurologically active amino acid that works by increasing brain activity in the alpha frequency band, which is associated with relaxing the mind without inducing drowsiness.66Nobre AC, Rao A, Owen GN. L-theanine, a natural constituent in tea, and its effect on mental state. Asia Pac J Clin Nutr 2008;17 Suppl 1:167-8. Various studies have examined the effects of this amino acid on stress and anxiety67Kimura K, Ozeki M, Juneja LR, Ohira H. L-Theanine reduces psychological and physiological stress responses. Biol Psychol 2007;74(1):39-45 68Unno K, Tanida N, Ishii N, et al. Anti-stress effect of theanine on students during pharmacy practice: positive correlation among salivary α-amylase activity, trait anxiety, and subjective stress. Pharmacol Biochem Behav. 2013 Oct;111:128-35. 69Yoto A, Motoki M, Murao S, Yokogoshi H. Effects of L-theanine or caffeine intake on changes in blood pressure under physical and psychological stresses. J Physiol Anthropol. 2012 Oct 29;31:28. 70Higashyama A, Htay HH, Ozeki M, Juneja LR, Kapoor MP. Effects of L-theanine on attention and reaction time response. Journal of Functional Foods. 2011;3(3):171–178., demonstrating its effectiveness in reducing physiological indicators of stress within 15 minutes, reductions in heart rate, inhibition of cortical neuron excitation, suppressing the initial stress response, and significantly reducing stress-induced anxiety.
Magnesium
Magnesium is an essential mineral involved in over 300 metabolic reactions, including energy production, nerve and muscle function, and sleep regulation. It may also help prevent or delay age-related physical decline.71Rude RK, Shils ME. Magnesium. In: Shils ME, Shike M, Ross AC, Caballero B, Cousins RJ, eds. Modern Nutrition in Health and Disease. 10th ed. Baltimore: Lippincott Williams & Wilkins; 2006:223-247. Magnesium supplementation has been shown to support mood and reduce stress, particularly in individuals experiencing stress-related symptoms. Research72Pickering G, Mazur A, Trousselard M, Bienkowski P, Yaltsewa N, Amessou M, Noah L, Pouteau E. Magnesium Status and Stress: The Vicious Circle Concept Revisited. Nutrients. 2020 Nov 28;12(12):3672. doi: 10.3390/nu12123672. PMID: 33260549; PMCID: PMC7761127. suggests a “vicious circle” where stress can deplete magnesium levels, and magnesium deficiency can worsen stress responses.
Vitamin D3
In addition to the previous benefits associated with vitamin D3, this nutrient may also help with seasonal mood considerations. Reduced daylight during colder months can lead to lower serotonin production, which may negatively affect emotional well-being. Clinical studies suggest that vitamin D supplementation may help counteract these effects, improving mood in individuals with low vitamin D status or seasonal mood concerns.73Gloth, F. M., III, Alam, W., and Hollis, B. Vitamin D vs broad spectrum phototherapy in the treatment of seasonal affective disorder. J Nutr Health Aging 1999;3(1):5-7.
Melatonin
Melatonin, like vitamin D, is involved in regulating mood during winter months. With less daylight, the body produces more melatonin, which increases the conversion of serotonin into melatonin, reducing available serotonin and potentially impacting mood. In human clinical research74Lewy AJ, Bauer VK, Cutler NL, Sack RL. Melatonin treatment of winter depression: a pilot study. Psychiatry Res 1998;77:57-61. 75Leppamaki, S., Partonen, T., Vakkuri, O., Lonnqvist, J., Partinen, M., and Laudon, M. Effect of controlled-release melatonin on sleep quality, mood, and quality of life in subjects with seasonal or weather-associated changes in mood and behaviour. Eur.Neuropsychopharmacol. 2003;13(3):137-145., supplementation with melatonin resulted in mood enhancement associated with seasonal mood considerations.
It’s also worth noting that phytomelatonin, a natural, plant-based alternative to synthetic melatonin, is gaining popularity. Derived from sources like tomato and St. John’s Wort extracts, phytomelatonin has been shown in human studies to be equally, or even more, effective at lower doses compared to synthetic melatonin.76Bruno G, et al. A randomized, double-blind, placebo-controlled study to evaluate the effects of Somnatural™ 1mg and 3mg capsules and synthetic melatonin 10mg capsules on sleep quality and overall health outcomes. Radicle Science. Unpublished; 2024.
Supplement Manufacturing Trends to Watch in Winter 2026
Beyond individual ingredients, broader dietary supplement trends related to manufacturing are helping shape the nutraceutical industry in Winter 2026. These trends include the growing demand for convenient supplement formats and continued innovation in formulation, both of which reflect evolving consumer expectations around usability, efficacy, and product experience.
Convenient Supplement Formats
Emerging nutraceutical trends continue to highlight the growing popularity of convenient supplement formats as alternatives to traditional pills and bulk powders. These include chewable tablets, effervescent tablets, fast-melt tablets, and single-serving sachets or stick-packs.
One reason for their appeal is that up to 40% of the population struggles with swallowing pills, while others experience “pill fatigue” from taking multiple medications or supplements daily. These innovative formats offer a more user-friendly, accessible option for delivering key nutrients without compromising efficacy or compliance.
Innovations in Supplement Formulation
Many of the newer, convenient supplement formats also offer improved bioavailability. For individuals with compromised digestion or difficulty breaking down traditional tablets, options like chewables, fast melts, and effervescents may be more effective, as they begin breaking down before swallowing.
Other notable advances include time-release and delayed-release technologies. Time-release formulations allow for a controlled, sustained delivery of nutrients, which are ideal for ingredients like vitamin C, because it has multiple absorption sites in the gastrointestinal tract. Releasing it gradually may help enhance absorption throughout the gut.
Delayed-release formulations are especially useful for nutrients that require targeted timing. For example, a delayed-release melatonin supplement can provide a second wave of release a few hours after the initial dose, potentially helping extend its sleep-support effects. These innovations support both efficacy and personalized supplementation strategies.
Conclusion
As demand for wellness solutions continues to rise, dietary supplement makers must stay ahead by aligning their product strategies with evolving winter supplement trends.
From immune and mood support to beauty-from-within and plant-based nutrition, consumers are increasingly seeking innovative formulas that address seasonal health needs. Meeting these expectations requires a commitment to quality supplement manufacturing, where ingredient selection, delivery format, and efficacy are thoughtfully integrated. Whether you’re launching your brand for the first time or looking to expand your existing product line, Winter 2026 presents a prime opportunity to capitalize on emerging trends and consumer demand. From choosing the right vitamin manufacturing partner to exploring innovative delivery formats and scaling nutraceutical manufacturing capabilities, success in today’s market hinges on informed decision-making and strategic execution.
Are you ready to capitalize on the Winter 2026 Supplements Trends discussed in this article? If so, call 800-526-9095 to speak with one of our knowledgeable sales executives or request a nutraceutical manufacturing price quote if you’ve already finalized your project requirements!
Frequently Asked Questions About the Winter 2026 Supplement Trends
What are the top supplements consumers demand during winter?
Supplements for immune/respiratory support are also popular during the winter. These include vitamin C, zinc, elderberry, Echinacea, and NAC. Beauty from within supplements are likewise popular during the dry winter months, including collagen, hyaluronic acid, biotin, spermidine, and vitamin E. During the stressful holiday season, stress and mood support supplements, such as adaptogens, theanine, magnesium, vitamin D3, and melatonin, increase in popularity.
Why are vegan supplements gaining popularity in winter 2026?
Consumers perceive supplements made from natural, plant-based ingredients as gentler on the body and more easily absorbed, as well as better for health and environmental sustainability. As alternatives to animal-sourced supplements, vegan supplements gaining popularity in the winter months include vegan vitamin D3, vegan protein, and vegan collagen (which is a combination of vegan-sourced amino acids whose profile closely aligns with the amino acid profile of actual animal-sourced collagen).
What makes time-release supplements ideal for winter?
Time releasing can provide a predictable pattern of release for specific nutraceuticals, especially vitamin C, which is good for immune health, and so more popular during the winter season. Consider that vitamin C has multiple absorption sites in the gut, and that time-released vitamin C can release that nutrient at different gut locations to potentially maximize absorption.
How can supplement brands take advantage of winter 2026 trends?
It takes time to have dietary supplements manufactured. This is especially true if you’re using a high-quality contract development and manufacturing organization (CDMO) that does things right. That means you’ll need to begin planning at least six months in advance to produce supplements that will be popular during the winter season. These may include immune/respiratory support supplements, beauty from within supplements, and stress and mood support supplements.
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